Rewiring monocyte glucose metabolism via C-type lectin signaling protects against disseminated candidiasis
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چکیده
منابع مشابه
Rewiring monocyte glucose metabolism via C-type lectin signaling protects against disseminated candidiasis
Monocytes are innate immune cells that play a pivotal role in antifungal immunity, but little is known regarding the cellular metabolic events that regulate their function during infection. Using complementary transcriptomic and immunological studies in human primary monocytes, we show that activation of monocytes by Candida albicans yeast and hyphae was accompanied by metabolic rewiring induce...
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ژورنال
عنوان ژورنال: PLOS Pathogens
سال: 2017
ISSN: 1553-7374
DOI: 10.1371/journal.ppat.1006632